Katherine Duncan Aimone was born in Raleigh, North Carolina. She earned her undergraduate degrees in painting and German language at Georgia Southern University, and her MA in art history from Florida State University. She studied painting in Cortona, Italy for a summer as a part of her studies.

After graduate work, she focused on a career in museum curatorial work and consequently worked as a museum professional for 15 years at various institutions, both as a curator and a director.

She eventually moved back to her native state of North Carolina to work in Asheville as an editor/writer for Lark Books (Sterling Publishing, NY). Aimone's name is on the cover of many of the company's books, including The Fiberarts Book of Wearable Art. Throughout her career, she has written essays for artists as well as art-related articles for newspapers and magazines.

Aimone pursued painting during her spare time, and four years ago she committed herself to pursuing it professionally. During 2010 she has shown in two-person exhibitions at the Asheville Area Arts Council in Asheville, North Carolina and at Village Studios & Gallery in Greenville, South Carolina. She is currently involved in creating a body of work to show in galleries and museums.

Since 2001, she and her husband Steven Aimone have owned and operated Aimone Art Services. The company provides workshops, coaching, critique, and writing for artists. The Aimones divide their time between Asheville, North Carolina, and Monhegan Island, Maine.