Nathan Budoff earned his BFA at the University of Massachusetts, and an MFA at the School of the Art Institute of Chicago, as well as degrees in law and psychology. He received a Fulbright Fellowship and spent a year in Bogotá, Colombia. For over twenty-five years he has lived in San Juan, Puerto Rico. His recent visual art imagines living creature spaces and relationships, often unexpected, focusing on flora and fauna.

His artwork has been included in exhibitions in San Juan, Medellin, New York, Chicago, Minnesota, Santa Fe, Albuquerque, and Orlando. He recently had one-person exhibitions at Pie Projects in Santa Fe, NM, the Museo de Arte y Diseño de Miramar in San Juan, Puerto Rico and the Rollins Art Museum (in collaboration with Frances Gallardo) in Winter Park, Florida. His work is currently included in Vivarium, at the Albuquerque Museum.

Budoff painted a mural cycle on the four sides of the 45-foot-high pyramid in Cataño, Puerto Rico, titled Entre Tierra Firme y Mar, and created a 42-foot diameter byzantine mosaic, Con las Cotorras, on the ceiling of the Martínez Nadal Station of the San Juan metro. He has developed murals with students in Medellín, Colombia and San Juan, Puerto Rico, and incarcerated youth in Santa Fe, New Mexico. He has been an artist in residence at the Ucross Foundation, the Vermont Studio Center, the American Academy in Rome and the Faculty Resource Network at New York University. In addition to creating artwork, Budoff works with language, semiotics and translation.